A 30yearold woman was referred to our institution for apicoectomies of the. Florid cemento osseous dysplasia fcod is a rare, benign lesion affecting both the jaws. Cemento osseous dysplasia is a fairly common lesion of the jaws originating from the elements of the periodontal ligament. Clinically, the florid cemento osseous dysplasia is asymptomatic. Florid cemento osseous dysplasia fcod has been described as a condition that typically affects middleaged black women, and usually manifests as multiple radiopaque cementumlike masses distributed throughout the jaws. Clinical, radiographic, biochemical and histological. Florid cementoosseous dysplasia fcod is a benign fibro osseous lesion that primarily affects the jaws of middleaged women of african ancestry. Cod occurs in the toothbearing areas of the jaws and is probably the most common fibro osseous lesion encountered in clinical practice.
Florid cemento osseous dysplasia fcod is a well recognized fibro osseous disease of the jaws commonly seen in the middle aged african women, although it may occur in the caucasians and asians. This type must be differentiated from pagets disease, chronic diffuse osteomyelitis, and gardners syndrome. Several root canals were completed by her dentist 4 years ago. Case presentation of florid cementoosseous dysplasia with. Florid cemento osseous dysplasia 57 did not seem to be related to a simple bone cyst. Frequencies of the variables were described according to. In the present case no familial aspects of the disease could be established. Flcod was first comprehensively described by melrose et al. Florid cemento osseous dysplasia is more commonly seen in middleaged black women, although it also may occur in caucasians and asians 5,6. Jun 27, 20 florid osseous dysplasia fod is the most dramatic and rare variant of the cemento osseous lesions in which the normal cancellous bone is replaced by dense, acellular cemento osseous tissue in a background of fibrous connective tissue. Florid cementoosseous dysplasia pubmed central pmc. Extensive sclerotic masses of florid cementoosseous.
Florid cementoosseous dysplasia has been described as a condition that characteristically affects the jaws of middleaged black women. Misdiagnosis of florid cementoosseous dysplasia leading to. The term cemento osseous dysplasia is a histopathological term, yet the diagnosis can be made by clinical and radiographic findings1. Florid cemento osseous dysplasia was first described by melrose et al. Findings of florid cementoosseous dysplasia journal of oral.
Cemento osseous dysplasia is probably the most common fibro osseous lesion encountered in clinical practice. Pdf florid cemento osseous dysplasia fcod is a fibro osseous lesion that affects jaw bones of middleaged women affecting two or more quadrants of. Periapical cementoosseous dysplasia registered dental. Florid cementosseous dysplasia of maxilla and mandible. It is most commonly seen between the third and fourth decades of life 26, and is more frequent in women than in. This lesion is most commonly found in middleaged black women, although it may also occur in. Failure of dental implants in cemento osseous dysplasia. Clinical, radiographic, and histological findings of florid.
Of oral and maxillofacial radiology, faculty of dentistry, hamadam university of medical science, hamadam, iran imaging sci dent. Misdiagnosis of florid cementoosseous dysplasia leading. May 07, 2014 jc 1 cbct findings of periapical cementoosseous dysplasia 1. A case of florid cementoosseous dysplasia of the maxilla. On the other hand, clinical and histological evidences show this condition has a histogenetic origin derived from the periodontal ligament 29. Florid cementoosseous dysplasia fcod has been described as a condition that characteristically affects the jaws of middleaged black.
A 30yearold woman was referred to our institution for apicoectomies of the mandibular left canine and both the lateral incisors. Fcod refers to a set of radiolucentradiopaque periapical and interradicular lesions involving the mandible bilaterally and sometimes the maxilla. Florid cemento osseous dysplasia is an uncommon disease of the jaws. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree.
Lesions form symmetrically in the upper, lower, or both jaws, and can occasionally cause mild pain or discomfort. Cementoosseous dysplasia radiology reference article. Mar 14, 2020 lesions classified as cemento osseous dysplasia cod largely encompass three different subgroups. Nov 30, 2014 fibroosseous lesions the term fibroosseous lesion fol is a generic designation of a group of jaw disorders characterized by the replacement of bone by a benign connective tissue matrix. Introduction cemento ossifying fibroma is a benign fibro osseous maxillary tumor belonging to the same category as fibrous dysplasia and cementossifying dysplasia 1. The etiopathogenesis of fod is unknown but could derive from the periodontal ligament, the medullar bone or both 5. Florid cementoosseous dysplasia fcod is a rare, benign, fibroosseous, and multifocal dysplastic lesion of the jaw that consists of cellular fibrous connective tissue with bone and cementumlike tissue. Florid cementoosseous dysplasia radiology reference. A case report amir eskandarloo and faezeh yousefi dept. Benign fibroosseous lesions of the craniofacial complex a. The current who classification 2005 recommends use of the term florid osseous. Florid cementoosseous dysplasia may be confused with a simple bone cyst. The term florid osseous dysplasia was coined in 1976 by melrose et al.
Florid cementoosseous dysplasia genetic and rare diseases nih. Focal cementoosseous dysplasia fcod is a benign fibroosseous condition that can be seen in dentulous and edentulous patients. This article reports the case of a 49yearold black woman who was diagnosed with florid cemento osseous dysplasia on the basis. Cementoosseous dysplasia cod is a benign condition of the jaws that may arise from the fibroblasts of the periodontal ligaments. Florid cementoosseous dysplasia fcod is a type of fibro osseous lesion and represents a reactive process in which normal bone is replaced by poorly cellularized cementumlike materials and cellular fibrous connective tissues. Any aras of the jaws, but mainly in posterior mandible. Apart from neoplastic processes, chronic disfiguring and destructive diseases of the mandible are. Familial florid cementoosseous dysplasiaa case report. Here we present a case of 37yearold female patient, who reported for.
There is a reported incidence of less than 2% in the indian population. Cbct scans were retrospectively selected from a database of individuals who attended an oral medicine service. Pdf this report presents a case of florid cementoosseous dysplasia fcod, affecting the. Differentiating early stage florid osseous dysplasia from. Florid cement osseous dysplasia of maxilla and mandible.
Florid osseous dysplasia with superimposed mandibular. Florid osseous dysplasia with superimposed mandibular osteomyelitis, skeletal radiology, 2014, pp. Clinical, radiographic, and histological findings of. Pdf 2 florid cemento osseous dysplasia lawal adisa. Cooccurence of florid cemento osseous dysplasia and simple bone cyst. This matrix displays varying degrees of mineralization in the form of woven bone or of cementumlike round acellular intensely basophilic structures. Florid cementoosseous dysplasia fcod has been described as a condition that characteristically affects the jaws of middleaged black women. All three types are asymptomatic, and the patient is usually unaware that any changes have occurred until a radiographic examination causes the clinician to. People with fcod develop lesions in the jaw, were spots of normal bone are replaced with a mix of connective tissue and abnormal bone.
Report of 2 cases article pdf available in journal of clinical and experimental dentistry 1011 november 2018 with 98 reads how we measure reads. It is an exuberant variant of cemento osseous dysplasia normally seen in multiple quadrants of the jaws. Focal cementoosseous dysplasia early stage ddmfr oral. Florid cementoosseous dysplasia may be familial with an autosomal dominant inheritance pattern, but there are only a few examples in the literature in which the familial pattern has been confirmed 1,3. Cementoosseous dysplasia definition of cementoosseous. This is the first report of the florid form of cemento osseous dysplasia in. Florid cemento osseous dysplasia is a subtype of fibrous osseous lesion that commonly appears in the jaws of middleaged black women.
All alternative names for fcod were used as search terms for two electronic databases, namely medline and. Florid osseous dysplasia fod is the most dramatic and rare variant of the cemento osseous lesions in which the normal cancellous bone is replaced by dense, acellular cemento osseous tissue in a background of fibrous connective tissue. Clinical, radiographic, biochemical and histological findings. Radiographically, florid cementoosseous dysplasia is characterized by multiple masses of mixed radiopaque structures. Florid osseous dysplasia fod is the most extensive form with bony lesions involving multiple quadrants of the jaws. It is found more commonly in middleaged black females and also in caucasians and asians. Florid cementoosseous dysplasia is one of the terms that have been designated by the world health organization as cementoosseous dysplasias of the jaws. Florid cementoosseous dysplasia fcod is a rare condition presenting in the jaws of unknown aetiology. Nov 14, 2018 florid cemento osseous dysplasia fcod is a condition that occurs in the jaw bone, especially close to where the teeth are formed. Florid cemento osseous dysplasia fcod is a sclerosing disease characterised by intense opaque masses with many irregular lobules and is generally observed in the jaws and the alveolar process. Cases with a confirmed diagnosis of periapical, focal, or florid cod were included. To describe the effects of cemento osseous dysplasia cod on anatomical structures. Clinical symptoms may occur due to secondary infection of exposed masses or may be due to mucosal irritation under prostheses. In some cases, a familial trend can be observed 710.
A 50yearold woman with osseous cementoosseous dysplasia odcod and osteomyelitis. These lesions exhibit a sclerotic appearance similar to that of other lesions on conventional radiographs. Background florid cemento osseous dysplasia fcod is a benign jaw lesion originating from periodontal ligament tissues usually asymptomatic and diagnosed accidentally at routine dental radiographic examination. Florid cemento osseous dysplasia may be familial with an autosomal dominant inheritance pattern, but there are only a few examples in the literature in which the familial pattern has been confirmed 1,3. N2 in 1986, a 60yearold african american woman visited the marquette university school of dentistry with a complaint of a vague, dull pain in her lower left quadrant.
The may have a circumferential radiolucency, primarily surrounding the root apices of vital teeth, and over time with the maturation of the lesions, they tend to become increasingly radiopaque. A surgical therapy was selected with removal of bone. Florid cemento osseous dysplasia and osteomyelitis for treatment purposes, the patient underwent hemato logical exams. It is classically described as a condition occurring almost exclusively in middle. Fibro osseous lesions of the jaws include fibrous dysplasia, ossifying fibroma, and cemento osseous dysplasia1. Florid cementoosseous dysplasia is a subtype of fibrousosseous lesion that commonly appears in the jaws of middleaged black women. Periapical cementoosseous dysplasia is asymptomatic, detected radiographically and usually requires no treatment. Fcod is a very rare condition presenting in the jaws. Cemento osseous dysplasia is a nonneoplastic process usually confined to the tooth bearing areas of jaws or edentulous alveolar process. The human skeleton undergoes full renewal every 1 to 4 years in children and cemnto to 10 years in adults. Cemento osseous dysplasia cod is a benign condition of the jaws that may arise from the fibroblasts of the periodontal ligaments. Cooccurence of florid cementoosseous dysplasia and.
Aug 23, 2019 cemento osseous dysplasia is a group of disorders known to originate from periodontal ligament tissues. This condition has been interpreted as a dysplastic lesion or developmental anomaly arising in toothbearing areas. Jc 1 cbct findings of periapical cementoosseous dysplasia. The term florid is used because of its widespread and extensive manifestation. A case report article pdf available in brazilian dental journal 204. Fibro osseous lesions classifications, pathophysiology.
Since a radiographic examination by her dentist showed radiopacity in the left side of the maxilla, she was referred to the department of dentistry and oral surgery. For this authors, periapical cemento osseous dysplasia or focal cemento osseous dysplasia are two different terms for the same reactive lesion. Panoramic a and periapical b radiographs show a mostly radiopaque odcod lesion accompanied by lamellar periosteal formation of new bone along the buccal surface of the mandible. The three types are periapical cemental dysplasia common in those of african descent, focal cementoosseous dysplasia caucasians, and florid cementoosseous dysplasia african descent. Pulp testing is an important tool in diagnosing periapical cementoosseous dysplasia, and limited. Florid osseous dysplasia fod is a very rare fibro osseous condition presenting in the jaws. Babu1, renita lorina castelino1 1department of oral and maxillofacial radiology, ab shetty memorial institute of dental sciences, nitte university, deralakatte, mangalore, karnataka, india. Fcod is most commonly found in middleaged black women, is generally asymptomatic, and is usually detected during radiological examination.
The use of hyperbaric oxygen therapy in actinomycotic. Most lesions do not have a hereditary basis, however a few familial cases have been documented. These lesions are most commonly seen in middleaged. Pdf to explore the demographic characteristics and clinical features among patients with osseous cementoosseous dysplasia odcod of the jaws and. Other cementoosseous dysplasias defined as lesions which share some of the features of periapical cemental dysplasia andor florid cementoosseous dysplasia, but do not have their characteristic clinicopathological patterns of presentation. Two oral and maxillofacial radiologists assessed the scans. A correct diagnosis of periapical cementoosseous dysplasia can be. Florid cemento osseous dysplasia consists of selflimiting lesions involving alveolar processes. Patients do not have laboratory or radiologic evidence of. It is thought to be a reactive phenomenon that arises from elements within the periodontal ligament. Fenerty s, shaw w, verma r, syed ab, kuklani r, yang j, ali s.
Pdf orthodontic treatment and cementoosseous dysplasia. Fibro osseous lesions of the jaws include fibrous dysplasia, ossifying fibroma, and cemento osseous dysplasia cod. Florid cementoosseous dysplasia fcod is a benign jaw lesion originating. Cemento osseous dysplasias are categorized into three types on basis of the clinical and radiographic features. Conebeam computed tomography analysis of cementoosseous.
This paper reports a case of a 15 year clinical and radiographic follow up of florid cemento osseous dysplasia. Florid cementoosseous dysplasia genetic and rare diseases. Radiographically, fcod appears as dense, lobulated masses, often symmetrically located in various regions of the jaws. Florid cemento osseous dysplasia clearly appears to be a form of bone and cemental dysplasia that is limited to the jaws. Concomitant occurrence of infected cementoosseous dysplasia. The patient was a 71yearold woman who had had a painless swelling in the left maxillary gingiva for 2 years. Till today, nearly 2% cases have been reported in the indians according to current literature 2. Florid cementoosseous dysplasia fcod is a condition that occurs in the jaw bone, especially close to where the teeth are formed. Florid cementoosseous dysplasia complicated by chronic. The word florid was introduced to describe the wide spread, extensive manifestations of the disease in the jaws.
The three types are periapical cemental dysplasia common in those of african descent, focal cemento osseous dysplasia caucasians, and florid cemento osseous. Florid osseous dysplasia definition of florid osseous. Florid cemento osseous dysplasia is a benign bone reactive process and represents a type of fibro osseous lesion, in which normal bone is replaced by fibrous connective tissues. The purpose of this paper is to report three cases diagnosed as fcod with their clinical, radiographic and histological findings. It appears to be a widespread form of periapical cemental dysplasia pcd. The process may be totally asymptomatic and, in such. Florid cementoosseous dysplasia refers to a group of fibroosseous lesions which are exuberant, multiquadrant and arise from the toothbearing area of the jaws. In most instances, the disease affects the mandible bilaterally and may or may not show concomitant maxillary involvement.
This lesion may be completely asymptomatic and in such cases the lesion is detected incidentally in radiographs. Patients do not have laboratory or radiologic evidence of bone disease in. Based on all the above information, a diagnosis of florid cemento osseous dysplasia fcod was made. If you have problems viewing pdf files, download the latest version of adobe reader. Florid osseous dysplasia fod, which was first described by melrose in 1976, is a rare benign lesion.
The lesions are often found in equal numbers and size on both sides of the jaw. It is usually a solitary fibro cemento osseous lesion. The etiology and pathogenesis of this entity are still unknown. For language access assistance, contact the ncats public information officer. Cooccurence of florid cementoosseous dysplasia and simple. Other cemento osseous dysplasias defined as lesions which share some of the features of periapical cemental dysplasia andor florid cemento osseous dysplasia, but do not have their characteristic clinicopathological patterns of presentation. Cooccurence of florid cementoosseous dysplasia and simple bone cyst. Jan 17, 2012 florid cemento osseous dysplasia fcod has been described as a condition that characteristically affects the jaws of middleaged black women. We report a case of florid cemento osseous dysplasia of the maxilla. It is an asymptomatic lesion and needs no treatment. Florid cemento osseous dysplasia fcod, described by melrose et al. Florid cementoosseous dysplasia clearly appears to be a form of bone and cemental dysplasia that is limited to jaws. The lesion can be seen opposite the mandibular left first molar in a standard occlusal radiograph of the. Florid cemento osseous dysplasia clearly appears to be a form of bone and cemental dysplasia that is limited to jaws.
We present a rare case of florid cementoosseous dysplasia fcod occurring in a 27yearold indian woman. Florid cementoosseous dysplasia in a young indian woman. When lesions with radiologic and microscopic features similar to fcod extend to two or more quadrants of the jaw, the disease is termed florid cemento osseous dysplasia flcod 112120. No clear definition indicates that when the multiple lesions of pcd can be. Material and methods case records of fcod and osteomyelitis over a 3 years period were retrieved, reassessed for confirmation of.
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